这一系列肽的抗菌活性为Cn-AMP1>Cn-AMP2>Cn-AMP3。Cn-AMP1还表现出抗真菌、抗癌和免疫调节活性(Silva等人,2012年)。Cn-AMP1(植物来源的椰子抗菌肽1)具有抗菌活性。Cn-AMP1(植物来源的椰子抗菌肽1)的来源是绿色椰子水,即椰子(Cocosnucifera)。
The antibacterial activity of this series of peptides is Cn-AMP1 > Cn-AMP2 > Cn-AMP3. Cn-AMP1 also displayed antifungal, anticancer, and immune modulating activity (Silva et al. 2012). Cn-AMP1 (C. nucifera antimicrobial peptide 1, plants) has Antimicrobial activity. The source of Cn-AMP1 (C. nucifera antimicrobial peptide 1, plants) is green coconut water, Cocos nucifera.
单字母: H2N-SVAGRAQGM-OH
多字母: H2N-Ser-Val-Ala-Gly-Arg-Ala-Gln-Gly-Met-OH
氨基酸个数: 9
分子式:C34H61N13O12S1
平均分子量(MW): 875.99
精确分子量(Exact Mass)(MW): 875.43
等电点(PI): -
pH=7.0时的净电荷数: 1.97
GRAVY: 0.01
亲水残基比例: -
消光系数: -
溶解建议: 疏水
参考文献:
Mandal SM, Dey S, Mandal M, Sarkar S, Maria-neto S, Franco OL. Identification and structural insights of three novel antimicrobial peptides isolated from green coconut water. Peptides. 2009;30(4):633-7.
Anaya K, Podszun M, Franco OL, de Almeida Gadelha CA, Frank J. The Coconut Water Antimicrobial Peptide CnAMP1 Is Taken up into Intestinal Cells but Does Not Alter P-Glycoprotein Expression and Activity. Plant Foods Hum Nutr. 2020 Sep;75(3):396-403.