Defensin 5 (human)别名Defensin HD 5, HD 5, Human α-defensin 5, α-Defensin 5 (human)，是肠道微生物区体内稳态的关键调剂剂。Defensin 5 (human)由小肠内的帕内特细胞(Paneth cells)释放，对细菌，真菌和病毒显示出抗生活性。肠内粘膜Defensin 5 (human)释放的减少或者消失与肠道病原体过敏，微生物组成的改变和肠内免疫体内稳态的紊乱有关系。作为生物标记物，Defensin 5 (human)可能被用来区分溃疡性结肠炎(低水平Defensin 5 (human))还是克罗恩结肠炎(高水平Defensin 5 (human))。

单字母：ATCYCRTGRCATRESLSGVCEISGRLYRLCCR(Disulfide bonds, air oxidized)

多字母：H-Ala-Thr-Cys-Tyr-Cys-Arg-Thr-Gly-Arg-Cys-Ala-Thr-Arg-Glu-Ser-Leu-Ser-Gly-Val-Cys-Glu-Ile-Ser-Gly-Arg-Leu-Tyr-Arg-Leu-Cys-Cys-Arg-OH(Disulfide bonds, air oxidized)
分子式:  C144H238N50O45S6
分子量:  3582.18

应用：Antimicrobial & Antiviral Peptides

参考文献：
Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts【 DOI: 10.1016/s1097-2765(05)00092-4】