Lactoferricin B25

描 述：Lactoferrin 17-41 (Lactoferricin B) 对应于牛乳铁蛋白的残基 17-41，对革兰氏阳性和革兰氏阴性细菌、病毒、原生动物和真菌等多种微生物具有抗菌活性。Lactoferrin 17-41 具有抗肿瘤活性。

CAS号：146897-68-9

单字母：H2N-FKCRRWQWRMKKLGAPSITCVRRAF-OH(Disulfide Bridge:C3-C20)

多字母：H2N-Phe-Lys-Cys-Arg-Arg-Trp-Gln-Trp-Arg-Met-Lys-Lys-Leu-Gly-Ala-Pro-Ser-Ile-Thr-Cys-Val-Arg-Arg-Ala-Phe-OH(Disulfide Bridge:Cys3-Cys20)

氨基酸个数：25

分子式：C141H224N46O29S3

平均分子量(MW)：3123.77

精确分子量(Exact Mass)(MW)：3121.66

等电点(PI)：-

pH=7.0时的净电荷数：10.91

GRAVY：-0.58

亲水残基比例：0.11

消光系数：11000

溶解建议：亲水

参考文献：

   [1]. Samuelsen Ø, et al. Anti-complement effects of lactoferrin-derived peptides. FEMS Immunol Med Microbiol. 2004 Jun 1;41(2):141-8.

    [2]. Jiang R, et al. Bovine lactoferrin and lactoferricin exert antitumor activities on human colorectal cancer cells(HT-29) by activating various signaling pathways. Biochem Cell Biol. 2017 Feb;95(1):99-109.

    [3]. Latorre D, et al. Reciprocal interactions between lactoferrin and bacterial endotoxins and their role in the regulation of the immune response. Toxins (Basel). 2010;2(1):54‐68.