| Catalog No. |
TD-RP30892 |
| Synonyms |
Orexin B, mouse/rat |
| Description |
Orexins are synthesized by posterolateral neurons in hypothalamus. They bind to orexin-1 (OxR1) and orexin 2 (OxR2) receptors. Orexin A can bind to both OxR1 and OxR2 while Orexin B can associate with OxR2 only. Both Orexins are involved in the regulation of arousal and sleep states, energy homeostasis, and autonomic central control. |
| Sequence |
{Arg}{Pro}{Gly}{Pro}{Pro}{Gly}{Leu}{Gln}{Gly}{Arg}{Leu}{Gln}{Arg}{Leu}{Leu}{Gln}{Ala}{Asn}{Gly}{Asn}{His}{Ala}{Ala}{Gly}{Ile}{Leu}{Thr}{Met} |
| Sequence Shortening |
RPGPPGLQGRLQRLLQANGNHAAGILTM |
| C Terminal |
Amidation |
| Molecular Formula |
C₁₂₆H₂₁₅N₄₅O₃₄S |
| Molecular Weight |
2936.45 |
| Length |
28 |
| Purity |
>95% |
| Solubility |
Soluble in Ultrapure water under 1mg/ml |
| Form |
Lyophilized |
| Storage |
Store at -20°C. Keep tightly closed. Store in a cool dry place. |