Tulisokibart(TD-HF526016) is a research-grade recombinant antibody targetingTNFSF15. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
Species reactivity
Human
Applications
ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Protein A/G purified from cell culture supernatant.
Accession
O95150
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names
2648504-55-4
Background
Duvakitug is a humanized IgG1-λ2 monoclonal antibody targeting to TNFSF15/TL1A. Duvakitug' main expression system is CHOK1SV cells endogenously expressing glutamine synthetase (GS). Duvakitug can be used in the study of Crohn's Disease (CD).• Vascular endothelial growth inhibitor in human cancer (Review)., PMID:19513527• VEGI-192, a new isoform of TNFSF15, specifically eliminates tumor vascular endothelial cells and suppresses tumor growth., PMID:16061878
Caption
Detects TNFSF15/TL1A in indirect ELISAs. | Western blot analysis was performed using anti-TNFSF15 monoclonal antibody at 1μg/ml on various samples.Lane 1:recombinant human TNFSF15 (Catalog No:TD-HF526012), 50ngLane 2:recombinant human TNFSF15 (Catalog No:TD-HF526012), 30ngLane 3:recombinant human TNFSF15 (Catalog No:TD-HF526012), 20ngLane 4:recombinant human TNFSF15 (Catalog No:TD-HF526012), 10ng | SDS-PAGE for Research Grade Tulisokibart
Note
For research use only. Not suitable for clinical or therapeutic use.