Catalog No. |
TD-HF543026 |
Species reactivity |
Human |
Applications |
Research Grade Biosimilar |
Host species |
Humanized |
Isotype |
IgG4-kappa |
Expression system |
Mammalian Cells |
Species |
Human |
Clonality |
Monoclonal |
Target |
NF-HEV, IL-1F11, C9orf26, IL-33, Interleukin-1 family member 11, IL33, Nuclear factor from high endothelial venules, NFHEV, Interleukin-33, IL1F11 |
Endotoxin level |
Please contact with the lab for this information. |
Purity |
>95% as determined by SDS-PAGE. |
Purification |
Protein A/G purified from cell culture supernatant. |
Accession |
O95760 |
Form |
Liquid |
Storage buffer |
0.01M PBS, pH 7.4. |
Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
Alternate Names |
REGN-3500, SAR-440340, CAS: 2226742-52-3 |
Background |
Itepekimab (REGN-3500) is an IgG4 monoclonal antibody against IL-33. Itepekimab reduced airway inflammation and related tissue damage in preliminary clinical studies. Itepekimab has potential effects in asthma, chronic obstructive pulmonary disease (COPD), and atopic dermatitis (AD). |
Note |
For research use only. Not suitable for clinical or therapeutic use. |