| Catalog No. |
TD-HF687066 |
| Species reactivity |
Human |
| Applications |
Research Grade Biosimilar |
| Host species |
Human |
| Isotype |
IgG4-kappa |
| Expression system |
Mammalian Cells |
| Clonality |
Monoclonal |
| Target |
CPAMD4, C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, Complement C5 |
| Endotoxin level |
Please contact the lab for this information. |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Purification |
Protein A/G, purified from cell culture supernatant. |
| Accession |
P01031 |
| Form |
Liquid |
| Storage buffer |
0.01M PBS,pH7.4. |
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names |
REGN-3918,CAS:2096328-94-6 |
| Background |
Pozelimab (REGN3918) is a fully human IgG4 anti-C5 monoclonal antibody. Pozelimab binds to C5 and C5 variants with high affinity and blocks complement-mediated hemolysis. Pozelimab can be used for the research of complement-mediated diseases. |
| Note |
For research use only. Not for use in clinical or therapeutic applications. |