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Research Grade Lampalizumab
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TD-HF697016_1.jpg
- Catalog： TD-HF697016
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： AFD,Anti-fD,Anti-FACTORD,FCFD4514S,RG7417,CAS:1278466-20-8
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规格：
1mg
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价格：
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Research Grade Lampalizumab
| Catalog No. | TD-HF697016 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Humanized |
| Isotype | Fab-G1-kappa |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | PFD, Adipsin, C3 convertase activator, Complement factor D, CFD, DF, Properdin factor D |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supern atant. |
| Accession | P00746 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | AFD,Anti-fD,Anti-FACTORD,FCFD4514S,RG7417,CAS:1278466-20-8 |
| Background | Lampalizumab (RG 7417) is a humanised monoclonal antibody targeting complement Factor D in the alternative complement pathway. Lampalizumab binds an exosite and sterically blocks Factor B access to the active site. Lampalizumab can be used for age-related macular degeneration (AMD) research. |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
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Detects CFD in indirect ELISAs. |