抗体
试剂盒
多肽
蛋白
组织芯片
产品中心
Product Center
Research Grade Gevokizumab
All
TD-HF943026_1.jpg
TD-HF943026_2.jpg
TD-HF943026_3.jpg
- Catalog： TD-HF943026
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： XOMA 052, CAS: 1129435-60-4
-
规格：
1mg
-
价格：
¥询价
定制服务咨询
Research Grade Gevokizumab
| Catalog No. | TD-HF943026 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Humanized |
| Isotype | IgG2-kappa |
| Expression system | Mammalian Cells |
| Species | Human |
| Clonality | Monoclonal |
| Target | Interleukin-1 beta, IL1B, Catabolin, IL1F2, IL-1 beta |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P01584 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Alternate Names | XOMA 052, CAS: 1129435-60-4 |
| Background | Gevokizumab is a potent anti-IL-1β antibody, negatively modulates IL-1β signaling through an allosteric mechanism. Gevokizumab selectively decreases the binding affinity of IL-1β for the IL-1 receptor type I (IL-1RI) signaling receptor instead of IL-1 counter-regulatory decoy receptor (IL-1 receptor type II). |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
|
|
SEC-HPLC detection for Research Grade Gevokizumab. |
|
|
Detects Human IL1B/IL1F2 in indirect ELISAs. |
|
|
SDS-PAGE for Research Grade Gevokizumab. |