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Research Grade Fresolimumab
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- Catalog： TD-HF977016
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： GC-1008, CAS: 948564-73-6
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规格：
1mg
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价格：
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Research Grade Fresolimumab
| Catalog No. | TD-HF977016 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Human |
| Isotype | IgG4-kappa |
| Expression system | Mammalian Cells |
| Species | Human |
| Clonality | Monoclonal |
| Target | Transforming growth factor beta-1 proprotein, LAP, TGF-beta-1, TGFB1, TGFB |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P01137 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Alternate Names | GC-1008, CAS: 948564-73-6 |
| Background | Fresolimumab (GC1008) is a human monoclonal antibody against TGF-β that neutralizes all mammalian active subtypes of TGF-β. The binding affinity of Fresolimumab to TGF-β2 is 1.8 nM. Fresolimumab radiolabeled with 89Zr can be used for PET analysis of TGF-β expression, antibody uptake and organ distribution. Fresolimumab can be used in the study of cancer, osteogenesis imperfecta, fibrosis and kidney disease. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
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SEC-HPLC detection for Research Grade Fresolimumab. |
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Detects Human TGFB1/TGF-beta-1 in indirect ELISAs. |
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SDS-PAGE for Research Grade Fresolimumab. |