Ulviprubart(TD-HP013016) is a research-grade recombinant antibody targetingMast cell function-associated antigen. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
Species reactivity
Human
Applications
ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species
Human
Isotype
IgG1-kappa
Clonality
Monoclonal
Target
Mast cell function-associated antigen, Killer cell lectin-like receptor subfamily G member 1, C-type lectin domain family 15 member A, MAFA, CLEC15A, KLRG1, MAFA-like receptor, ITIM-containing receptor MAFA-L, MAFAL
Endotoxin level
Please contact the lab for this information.
Purity
>95% purity as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q96E93
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names
2569434-60-0
Background
Ulviprubart (ABC-008) is a monoclonal antibody targeting the KLRG1 receptor that selectively depletes highly differentiated cytotoxic T cells. Ulviprubart can be used in the study of inclusion body myositis (IBM).• MAFA-L, an ITIM-containing receptor encoded by the human NK cell gene complex and expressed by basophils and NK cells., PMID:9842918
Caption
SDS-PAGE for Research Grade Ulviprubart
Note
For research use only. Not suitable for clinical or therapeutic use.