| Catalog No. |
TD-HP572016 |
| Species reactivity |
Human |
| Applications |
Research Grade Biosimilar |
| Host species |
Humanized(Lama/glama) |
| Isotype |
VH-VH' |
| Expression system |
Mammalian Cells |
| Clonality |
Monoclonal |
| Target |
Thrombospondin type-1 domain-containing protein 6, ADAMTSL5, ADAMTS-like protein 5, THSD6, ADAMTSL-5, ALB, Albumin |
| Endotoxin level |
Please contact the lab for this information. |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Purification |
Protein A/G, purified from cell culture supernatant. |
| Accession |
Q6ZMM2 & P02768 |
| Form |
Liquid |
| Storage buffer |
0.01M PBS,pH7.4. |
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names |
Bispecific,M-6495,CAS:2254082-79-4 |
| Background |
Isecarosmab (M-6495) is an anti-ADAMTS monoclonal antibody (mAb) with a KD value of 3.65 pM. Isecarosmab has chondroprotective and anti-inflammatory activities. Isecarosmab can bind albumin to extend plasma half-life. |
| Note |
For research use only. Not for use in clinical or therapeutic applications. |