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Research Grade Bexmarilimab
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TD-HP617016_1.jpg
- Catalog： TD-HP617016
- Clonality：
- Application： Research Grade Biosimilar
- Synonyms： FZD8-Fc,Frizzled8Fc,OMP-54F28,CAS:1391727-24-4
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规格：
1mg
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价格：
¥询价
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Research Grade Bexmarilimab
| Catalog No. | TD-HP617016 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Humanized |
| Isotype | IgG4-kappa |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | MS-1 antigen, STAB1, FEEL-1, FEEL1, Stabilin-1, KIAA0246, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1 |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | Q9NY15 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Background | Bexmarilimab (FP-1305) is a potent humanized anti-CLEVER-1 IgG4-antibody with an IC50 value of 4.51 nM. Bexmarilimab is capable of inducing a phenotypic M2 to M1 immune switch of tumor-associated macrophages. Bexmarilimab can be used in research of cancer. |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
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SEC-HPLC detection for Research Grade Bexmarilimab. |