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抗体药类似物
Research Grade Toripalimab
All
  • CatalogTD-HS870086
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsCAS:1924598-82-2
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Toripalimab


Catalog No. TD-HS870086
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype IgG4-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession Q15116
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names CAS:1924598-82-2
Background Toripalimab is the first domestic anti-tumor PD-1 antibody in China. Toripalimab is a selective, recombinant, humanized monoclonal antibody against PD-1. Toripalimab is able to bind to PD-1 and block the interaction with its ligands. Toripalimab has exhibited primary anti-tumor effects in tumors such as melanoma, lung cancer, digestive tract tumors, hepatobiliary and pancreatic tumors, neuroendocrine neoplasms, nasopharyngeal carcinoma and urothelial carcinoma.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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SEC-HPLC
 
SEC-HPLC detection for Research Grade Toripalimab.
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Bioactivity
 
Detects Human CD279/PDCD1/PD1 in indirect ELISAs.