EN
抗体药类似物
Research Grade Budigalimab
All
  • CatalogTD-HS870106
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsABBV-181,PR-1648817,CAS:2098225-93-3
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Budigalimab


Catalog No. TD-HS870106
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype IgG1-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession Q15116
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names ABBV-181,PR-1648817,CAS:2098225-93-3
Background Budigalimab (ABBV 181; PR 1648817) is a humanized, recombinant IgG1 monoclonal antibody targeting programmed cell death 1 (PD-1) receptor. Budigalimab has an Fc mutation that reduces the inhibition of Fc receptor interactions and effector factors. Budigalimab can block the binding of PD-1 and PD-L1, which has anti-tumor activity. Budigalimab can be used in the study of solid tumors.
Note For research use only. Not for use in clinical or therapeutic applications.