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抗体药类似物
Research Grade Camrelizumab
All
  • CatalogTD-HS870116
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsSHR-1210,CAS:1798286-48-2
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Camrelizumab


Catalog No. TD-HS870116
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype IgG4-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession Q15116
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names SHR-1210,CAS:1798286-48-2
Background Camrelizumab (SHR-1210) is a potent humanied high-affinity IgG4-κ monoclonal antibody (mAb) to PD-1. Camrelizumab binds PD-1 at a high affinity of 3 nM and inhibits the binding interaction of PD-1 and PD-L1 with an IC50 of 0.70 nM. Camrelizumab acts as anti-PD-1/PD-L1 agent and can be used for cancer research, including NSCLC, ESCC, Hodgkin lymphoma, and advanced HCC et,al.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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Bioactivity
 
Detects Human CD279/PDCD1/PD1 in indirect ELISAs.