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Research Grade Vudalimab
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TD-HS870226_1.jpg
- Catalog： TD-HS870226
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： Bispecific,XmAb-20717,XMAB20717,CAS:2329669-72-7
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规格：
1mg
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价格：
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Research Grade Vudalimab
| Catalog No. | TD-HS870226 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Humanized |
| Isotype | half-IGG1-kappa/(scFv-kappa-heavy)-h-CH2-CH3 |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279, CD152, Cytotoxic T-lymphocyte protein 4, CTLA-4, CTLA4, Cytotoxic T-lymphocyte-associated antigen 4 |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | Q15116 & P16410 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | Bispecific,XmAb-20717,XMAB20717,CAS:2329669-72-7 |
| Background | Vudalimab is a potent dual PD-1 and CTLA-4 inhibitor as a fully humanized bispecific monoclonal antibody. Vudalimab targets immune checkpoint receptors PD-1 and CTLA-4 and promotes tumor-selective T-cell activation. |
| Note | For research use only. Not for use in clinical or therapeutic applications |
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Detects CD279/PDCD1/PD1 in indirect ELISAs. |