EN
抗体药类似物
Research Grade Murlentamab
All
  • CatalogTD-HS882016
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • Synonyms3C23K,GM102,CAS:2058047-65-5
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Murlentamab


Catalog No. TD-HS882016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype IgG1-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target MIS type II receptor, MISR2, AMHR2, AMHR, Anti-Muellerian hormone type II receptor, MRII, AMH type II receptor, MISRII, Anti-Muellerian hormone type-2 receptor
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession Q16671
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names 3C23K,GM102,CAS:2058047-65-5
Background Murlentamab (3C23K; GM102) is a humanized anti-AMHRII antibody. AMHRII is the anti-Müllerian hormone receptor. Murlentama significantly promotes macrophage-mediated antibody-dependent cell-mediated cytotoxicity (ADCC). Murlentama stimulates pro-inflammatory and anti-tumor internal environment, recruits and activates T cells. Murlentama suppresses tumors growth by inducing naïve macrophage orientation and promoting tumor-associated macrophage (TAM) reprogramming.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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Bioactivity
 
SEC-HPLC detection for Research Grade Murlentamab.