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Research Grade Vanucizumab
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- Catalog： TD-HT073026
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： Bispecific,RG-7221,RG7221,RO5520985,CAS:1448221-05-3
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规格：
1mg
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价格：
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Research Grade Vanucizumab
| Catalog No. | TD-HT073026 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Humanized |
| Isotype | VH-C-kappa-CH2-CH3_V-lambda-CH1_H-GAMMA-1_L-kappa |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | Vascular endothelial growth factor A, VPF, VEGFA, VEGF, Vascular permeability factor, VEGF-A, ANG-2, ANGPT2, Angiopoietin-2 |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | P15692 & O15123 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | Bispecific,RG-7221,RG7221,RO5520985,CAS:1448221-05-3 |
| Background | Vanucizumab is a first-in-class, bispecific IgG1-like monoclonal antibody that simultaneously blocks VEGF-A and angiopoietin-2 (Ang-2) from interacting with their receptors. Vanucizumab has antiangiogenic and anticancer effects. |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
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Detects Human VEGFA in indirect ELISAs. |
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SEC-HPLC detection for Research Grade Vanucizumab. |
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Detects Human ANGPT2 in indirect ELISAs. |