Catalog No. |
TD-HT073096 |
Species reactivity |
Human |
Applications |
Research Grade Biosimilar |
Host species |
Human |
Isotype |
Fusion - IGHG1 Fc (Fragment constant) - [peptide 14-mer - peptide 14-mer]2 |
Expression system |
Mammalian Cells |
Target |
ANG-2, ANGPT2, Angiopoietin-2 |
Endotoxin level |
Please contact the lab for this information. |
Purity |
>95% purity as determined by SDS-PAGE. |
Purification |
Protein A/G, purified from cell culture supernatant. |
Accession |
O15123 |
Form |
Liquid |
Storage buffer |
0.01M PBS,pH7.4. |
Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
Alternate Names |
2xCon4C,AMG386 |
Background |
Trebananib (2xCon4C; AMG 386) is an Fc fusion peptibody that prevents Tie2 receptor activation through binding of both angiopoietin 1 (Ang1) and Ang2. Trebananib has anti-angiogenesis activity. |
Note |
For research use only. Not for use in clinical or therapeutic applications. |