Catalog No. |
TD-HT343066 |
Species reactivity |
Human |
Applications |
Research Grade Biosimilar |
Isotype |
Fusion - [ACVR2B (activin A receptor type 2B, ActR-IIB, ActRIIB)]2 - IGHG1 Fc (Fragment constant) |
Expression system |
Mammalian Cells |
Target |
GDF-8, GDF8, MSTN, Myostatin, Growth/differentiation factor 8 |
Endotoxin level |
Please contact the lab for this information. |
Purity |
>95% purity as determined by SDS-PAGE. |
Purification |
Protein A/G, purified from cell culture supernatant. |
Accession |
O14793 |
Form |
Liquid |
Storage buffer |
0.01M PBS,pH7.4. |
Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
Alternate Names |
ACE-031,ActRIIB-IgG1,ActRIIb:FcFusionProtein,HGT-4510,RAP-031,CAS:1169766-01-1 |
Background |
Ramatercept (ACE-031) is a soluble ActRIIB receptor and can be used as a soluble activin receptor 2 (ACVR2) antagonist. Ramatercept inhibits the signal pathway of muscle growth inhibition and has potential application in muscle atrophy. |
Note |
For research use only. Not for use in clinical or therapeutic applications. |