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抗体药类似物
Research Grade Benufutamab
All
  • CatalogTD-HT348016
  • Clonality
  • Application Research Grade Biosimilar
  • Synonyms
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Benufutamab


Catalog No. TD-HT348016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype IgG1-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target TRAILR2, TRAIL-R2, Death receptor 5, CD262, DR5, Tumor necrosis factor receptor superfamily member 10B, ZTNFR9, TRAIL receptor 2, TRICK2, TNFRSF10B, KILLER, TNF-related apoptosis-inducing ligand receptor 2
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession O14763
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names GEN1029,CAS:2109730-69-8
Background Benufutamab (GEN1029) is a death receptor 5 (DR5)-specific agonistic antibody. Benufutamab is a mixture of 2 noncompeting DR5-specific IgG1 antibodies, each with an E430G mutation in the Fc domain. Benufutamab has antitumor effects.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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Bioactivity
 
Detects Recombinant Human CD262/TNFRSF10B/DR5 Protein, C-His (Cat No.: TD-HT348021) in indirect ELISA.