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抗体药类似物
Research Grade Tigatuzumab
All
  • CatalogTD-HT348026
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsCS-1008,TRA-8,CAS:918127-53-4
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Tigatuzumab


Catalog No. TD-HT348026
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype IgG1-nd
Expression system Mammalian Cells
Clonality Monoclonal
Target TRAILR2, TRAIL-R2, Death receptor 5, CD262, DR5, Tumor necrosis factor receptor superfamily member 10B, ZTNFR9, TRAIL receptor 2, TRICK2, TNFRSF10B, KILLER, TNF-related apoptosis-inducing ligand receptor 2
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession O14763
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names CS-1008,TRA-8,CAS:918127-53-4
Background Tigatuzumab (CS-1008) is a humanized IgG1 monoclonal antibody targets death receptor 5 (DR5). Tigatuzumab induces cell apoptosis of cancer cells and inhibits tumor growth in vivo. Tigatuzumab can be used for the research of cancer.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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SEC-HPLC
 
SEC-HPLC detection for Research Grade Tigatuzumab.
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Bioactivity
 
Detects CD262/TNFRSF10B/TRAIL-R2/DR5 in indirect ELISAs.