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Research Grade Conatumumab
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- Catalog： TD-HT348036
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： AMG655,TRAIL-R2mAb,XG1-048vw,CAS:896731-82-1
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规格：
1mg
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价格：
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Research Grade Conatumumab
| Catalog No. | TD-HT348036 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Human |
| Isotype | IgG1-kappa |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | TRAILR2, TRAIL-R2, Death receptor 5, CD262, DR5, Tumor necrosis factor receptor superfamily member 10B, ZTNFR9, TRAIL receptor 2, TRICK2, TNFRSF10B, KILLER, TNF-related apoptosis-inducing ligand receptor 2 |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | O14763 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | AMG655,TRAIL-R2mAb,XG1-048vw,CAS:896731-82-1 |
| Background | Conatumumab (AMG 655) is a human monoclonal agonist antibody against human death receptor 5 (DR5, TRAILR2) (Kd: 1 nM for the long form of DR5, 0.8 nM for the short form of DR5). Conatumumab induces apoptosis via caspase activation. Conatumumab can be used in the research of cancers. . |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
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Detects CD262/TNFRSF10B/TRAIL-R2/DR5 in indirect ELISAs. |