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Research Grade Surzebiclimab
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- Catalog： TD-HV029036
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： BGB-A425,CAS:2342597-90-2
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规格：
1mg
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价格：
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Research Grade Surzebiclimab
| Catalog No. | TD-HV029036 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Humanized |
| Isotype | IgG1-Kappa |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | T-cell immunoglobulin mucin receptor 3, HAVcr-2, TIMD-3, T-cell membrane protein 3, HAVCR2, Hepatitis A virus cellular receptor 2, CD366, TIMD3, TIM-3, TIM3, T-cell immunoglobulin and mucin domain-containing protein 3 |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | Q8TDQ0 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | BGB-A425,CAS:2342597-90-2 |
| Background | Surzebiclimab (BGB-A425) is a humanized IgG1-variant monoclonal antibody against T-cell immunoglobulin and mucin-domain containing-3 (TIM-3). Surzebiclimab binds to the extracellular domain of human Tim-3 with high affinity (KD=0.36 nM) and specificity. Surzebiclimab can be used in research of cancer. |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
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Detects CD366/HAVCR2/TIM-3 in indirect ELISAs. |