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抗体药类似物
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Research Grade Latikafusp
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SDS-PAGE
  • Catalog： TD-HV076016
  • Clonality： Monoclonal
  • Application： ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Synonyms： Bispecificantibody, AMG256, AMG-256, AMG256, 2552814-07-8
  • 规格：
    询价
  • 价格：
    ¥100ug
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  • Catalog No.
    TD-HV076016
  • Description
    Latikafusp(TD-HV076016) is a research-grade recombinant antibody targetingCD360. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
  • Species reactivity
    Human
  • Applications
    ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Host species
    Human
  • Isotype
    IgG1-lambda2
  • Clonality
    Monoclonal
  • Target
    IL21R, NILR, Interleukin-21 receptor, IL-21R, IL-21 receptor, CD360, Novel interleukin receptor, Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279
  • Endotoxin level
    Please contact the lab for this information.
  • Purity
    >95% purity as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    Q9HBE5 & Q15116
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Alternate Names
    Bispecificantibody, AMG256, AMG-256, AMG256, 2552814-07-8
  • Background
    Latikafusp (AMG 256) is a bifunctional fusion protein comprising a PD-1-targeting antibody and IL-21 mutein designed to deliver IL-21 pathway stimulation to PD-1+ cells. Latikafusp is designed to prime and extend the activity of cytotoxic and memory T cells and induce anti-tumor immunity. Latikafusp has the potential for solid tumors research.Latikafusp may lead to the development of immunogenicity-mediated responses.
  • Caption
    SDS-PAGE for Research Grade Latikafusp
  • Note
    For research use only. Not suitable for clinical or therapeutic use.