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抗体药类似物
Research Grade Frovocimab
All
  • CatalogTD-HV275036
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsLY-3015014,CAS:1643672-70-1
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Frovocimab


Catalog No. TD-HV275036
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype IgG4-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target Proprotein convertase subtilisin/kexin type 9, Subtilisin/kexin-like protease PC9, NARC-1, PC9, Proprotein convertase 9, Neural apoptosis-regulated convertase 1, NARC1, PCSK9
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession Q8NBP7
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names LY-3015014,CAS:1643672-70-1
Background Frovocimab (LY 3015014) is a humanized IgG4 monoclonal antibody (mAb) that neutralizes PCSK9. Frovocimab inhibits PCSK9 binding to LDL receptor (LDLR) while permitting the normal proteolytic cleavage of the bound intact PCSK9.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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SEC-HPLC
 
SEC-HPLC detection for Research Grade Frovocimab.
TD-HV275036_2.jpg
Bioactivity
 
Detects Human PCSK9 in indirect ELISAs.