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Research Grade Tafolecimab
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- Catalog： TD-HV275076
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： IBI-306,CAS:2225109-03-3
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规格：
1mg
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价格：
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Research Grade Tafolecimab
| Catalog No. | TD-HV275076 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Human |
| Isotype | IgG2-kappa |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | Proprotein convertase subtilisin/kexin type 9, Subtilisin/kexin-like protease PC9, NARC-1, PC9, Proprotein convertase 9, Neural apoptosis-regulated convertase 1, NARC1, PCSK9 |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | Q8NBP7 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | IBI-306,CAS:2225109-03-3 |
| Background | Tafolecimab (IBI-306) is a human lgG2 monoclonal antibody that specifically binds PCSK-9 and reduces LDL-C levels by inhibiting PCSK-9-mediated endocytosis of the LDL receptor, which in turn enhances clearance of LDL-C and leads to a reduction in LDL-C levels. Tafolecimab may be used in studies of hypercholesterolaemia. |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
|
Bioactivity |
SEC-HPLC detection for Research Grade Tafolecimab. |