| Catalog No. |
TD-HV375016 |
| Species reactivity |
Human |
| Applications |
Research Grade Biosimilar |
| Host species |
Chimeric |
| Isotype |
IgG4-kappa |
| Expression system |
Mammalian Cells |
| Clonality |
Monoclonal |
| Target |
B- and T-lymphocyte attenuator, BTLA, CD272, B- and T-lymphocyte-associated protein |
| Endotoxin level |
Please contact the lab for this information. |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Purification |
Protein A/G, purified from cell culture supernatant. |
| Accession |
Q7Z6A9 |
| Form |
Liquid |
| Storage buffer |
0.01M PBS,pH7.4. |
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names |
JS004,Icatolimab,CAS:2236068-83-8 |
| Background |
Tifcemalimab (JS004) is a humanized anti-BTLA (B and T lymphocyte attenuation factor) monoclonal antibody. Tifcemalimab blocks the interaction of HVEM-BTLA by binding to BTLA, and thus blocks the inhibitory signaling pathway mediated by BTLA. Tifcemalimab can be used in research of cancer. |
| Note |
For research use only. Not for use in clinical or therapeutic applications. |