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Research Grade Guselkumab
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TD-HV466036_1.jpg
- Catalog： TD-HV466036
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： CNTO-1959,CAS:1350289-85-8
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规格：
1mg
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价格：
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Research Grade Guselkumab
| Catalog No. | TD-HV466036 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Human |
| Isotype | IgG1-lambda |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | SGRF, IL-23-A, IL-23 subunit alpha, Interleukin-23 subunit p19, IL23A, Interleukin-23 subunit alpha, IL-23p19 |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | Q9NPF7 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | CNTO-1959,CAS:1350289-85-8 |
| Background | Guselkumab is a recombinant human IgG1 monoclonal antibody against the IL-23p19 subunit. Guselkumab binds to human and cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab inhibits production of cytokines lying downstream of the IL-23 signaling pathway and can be used for psoriatic arthritis research. |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
|
Bioactivity |
SEC-HPLC detection for Research Grade Guselkumab. |