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抗体药类似物
Research Grade Brazikumab
All
TD-HV466046_1.jpg
  • CatalogTD-HV466046
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsAMG-139, MEDI2070, CAS: 1610353-18-8
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Brazikumab


Catalog No. TD-HV466046
Species reactivity Human
Applications Research Grade Biosimilar
Host species Human
Isotype IgG2-lambda
Expression system Mammalian Cells
Species Human
Clonality Monoclonal
Target SGRF, IL-23-A, IL-23 subunit alpha, Interleukin-23 subunit p19, IL23A, Interleukin-23 subunit alpha, IL-23p19
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q9NPF7
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternate Names AMG-139, MEDI2070, CAS: 1610353-18-8
Background Brazikumab (AMG 139) is a human IgG2 monoclonal antibody, selectively binds the p19 subunit of IL-23, with a KD of 0.138 nM for human IL-23. Brazikumab can be used for the research of Crohn's disease.
Note For research use only. Not suitable for clinical or therapeutic use.

 

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Bioactivity
 

SEC-HPLC detection for Research Grade Brazikumab.