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抗体药类似物
Research Grade Pepinemab
All
TD-HV563016_1.jpg
  • CatalogTD-HV563016
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsVX-15,VX15/2503,CAS:2097151-87-4
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Pepinemab


Catalog No. TD-HV563016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype IgG4-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target A8, Semaphorin-4D, GR3, BB18, SEMAJ, C9orf164, CD100, SEMA4D
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession Q92854
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names VX-15,VX15/2503,CAS:2097151-87-4
Background Pepinemab (VX 15/2503) is a human monoclonal antibody against SEMA4D, a signalling protein 4D (SEMA4D), also known as CD100, which is a regulator of neuronal development and plays a role in a variety of cellular processes. Pepinemab can be used in the study of various neurodegenerative diseases such as Alzheimer's disease by blocking the activity of SEMA4D.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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Bioactivity
 
Detects CD100/SEMA4D in indirect ELISAs.