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Research Grade Mirzotamab
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TD-HV612036_1.jpg
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- Catalog： TD-HV612036
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： ABBV-155,CAS:2229859-11-2
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规格：
1mg
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价格：
¥询价
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Research Grade Mirzotamab
| Catalog No. | TD-HV612036 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Humanized |
| Isotype | IgG1-kappa |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | CD276, B7-H3, Costimulatory molecule, B7H3, 4Ig-B7-H3, B7 homolog 3, CD276 antigen |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | Q5ZPR3 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | ABBV-155,CAS:2229859-11-2 |
| Background | Mirzotamab is an IgG1κ monoclonal antibody targeting to CD276/B7-H3 with anti-tumor activity. Mirzotamab conjugates with Clezutoclax (HY-137774), a BCL inhibitor to form Mirzotamab clezutoclax (HY-P99741), involving in research with taxane research in relapsed/refractory solid tumors. Mirzotamab clezutoclax (ABBV-155) is a targeted antibody drug conjugate (ADC). |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
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SEC-HPLC detection for Research Grade Mirzotamab. |
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Detects CD276/B7-H3 in indirect ELISAs. |