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抗体药类似物
Research Grade Obrindatamab
All
  • CatalogTD-HV612046
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsBispecific,MGD009,RES281M1.1,hBRCA84D-hXR32-MP3M1.1,CAS:2069959-72-2
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Obrindatamab


Catalog No. TD-HV612046
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype scFv with Domain Crossover,Kappa;Lambda
Expression system Mammalian Cells
Clonality Monoclonal
Target CD276, B7-H3, Costimulatory molecule, B7H3, 4Ig-B7-H3, B7 homolog 3, CD276 antigen, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession Q5ZPR3 & P07766
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names Bispecific,MGD009,RES281M1.1,hBRCA84D-hXR32-MP3M1.1,CAS:2069959-72-2
Background Obrindatamab is a humanized anti-B7-H3/CD3 bispecific antibody. Obrindatamab binds to B7-H3 and CD3, thereby mediating redirected cytotoxic T-lymphocyte (CTL) activity against B7-H3-expressing cancer cells. Obrindatamab can be used in research of cancer.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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SDS-PAGE for Research Grade Obrindatamab
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Detects CD276 in indirect ELISAs.
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Detects CD3E in indirect ELISAs.
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Detects CD276 in indirect ELISA.
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Detects Recombinant Human CD276 Protein, C-His (Cat No.: TD-HV612011) in indirect ELISA.