| Catalog No. |
TD-HV684016 |
| Species reactivity |
Human |
| Applications |
Research Grade Biosimilar |
| Host species |
Humanized |
| Isotype |
(scFv-heavy-lambda)-(scFv-heavy-lambda)-scFc |
| Expression system |
Mammalian Cells |
| Clonality |
Monoclonal |
| Target |
MUC-3, MUC-17, MUC17, Small intestinal mucin-3, Mucin-17, MUC3, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain |
| Endotoxin level |
Please contact the lab for this information. |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Purification |
Protein A/G, purified from cell culture supernatant. |
| Accession |
Q685J3 & P07766 |
| Form |
Liquid |
| Storage buffer |
0.01M PBS,pH7.4. |
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names |
Bispecific,AMG199,AMG-199,AMG199CAS:2413453-53-7 |
| Background |
Vepsitamab (AMG 199) is an anti-MUC17/CD3 BiTE antibody that binds to CD3 on T cells and MUC17 expressed on tumor cells, mediates redirected tumor cell lysis, and induces T cell activation and proliferation. |
| Note |
For research use only. Not for use in clinical or therapeutic applications. |