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抗体药类似物
Research Grade Vepsitamab
All
TD-HV684016_1.jpg
  • CatalogTD-HV684016
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsBispecific,AMG199,AMG-199,AMG199CAS:2413453-53-7
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Vepsitamab


Catalog No. TD-HV684016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype (scFv-heavy-lambda)-(scFv-heavy-lambda)-scFc
Expression system Mammalian Cells
Clonality Monoclonal
Target MUC-3, MUC-17, MUC17, Small intestinal mucin-3, Mucin-17, MUC3, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession Q685J3 & P07766
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names Bispecific,AMG199,AMG-199,AMG199CAS:2413453-53-7
Background Vepsitamab (AMG 199) is an anti-MUC17/CD3 BiTE antibody that binds to CD3 on T cells and MUC17 expressed on tumor cells, mediates redirected tumor cell lysis, and induces T cell activation and proliferation.
Note For research use only. Not for use in clinical or therapeutic applications.

 

TD-HV684016_1.jpg
Bioactivity
 
Detects Recombinant Human MUC17 Protein, N-His (Cat No.: TD-HV684012) in indirect ELISA.