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Research Grade Cevostamab
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TD-HV698016_1.jpg
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- Catalog： TD-HV698016
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： Bispecific,BFCR-4350-A,BFCR-4350A,RG-6160,RO-7187797,CAS:2249888-53-5
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规格：
1mg
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价格：
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Research Grade Cevostamab
| Catalog No. | TD-HV698016 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Humanized |
| Isotype | IgG1-kappa |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | FcRL5, FCRH5, FCRL5, Fc receptor homolog 5, FcRH5, CD307e, FcR-like protein 5, IRTA2, Immune receptor translocation-associated protein 2, BXMAS1, Fc receptor-like protein 5, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | Q96RD9 & P07766 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | Bispecific,BFCR-4350-A,BFCR-4350A,RG-6160,RO-7187797,CAS:2249888-53-5 |
| Background | Cevostamab (BFCR4350A; RG6160; RO7187797) is a humanized IgG1-based BsAb that targets membrane-proximal extracellular domain of FcRH5 on multiple myeloma (MM) cells as well as CD3 on T cells. Moreover, Cevostamab facilitates efficient synapse formation, improves killing activity of T cells against MM tumor cells. |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
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SDS-PAGE for Research Grade Cevostamab |
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SEC-HPLC detection for Research Grade Cevostamab. |