Catalog No. |
TD-HV702046 |
Species reactivity |
Human |
Applications |
Research Grade Biosimilar |
Host species |
Humanized |
Isotype |
half-IGG1-kappa/(scFv-kappa-heavy)-h-CH2-CH3 |
Expression system |
Mammalian Cells |
Clonality |
Monoclonal |
Target |
CD278, ICOS, Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, AILIM, Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279 |
Endotoxin level |
Please contact the lab for this information. |
Purity |
>95% purity as determined by SDS-PAGE. |
Purification |
Protein A/G, purified from cell culture supernatant. |
Accession |
Q9Y6W8 & Q15116 |
Form |
Liquid |
Storage buffer |
0.01M PBS,pH7.4. |
Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
Alternate Names |
Bispecific,XmAb-23104,CAS:2329669-80-7 |
Background |
Izuralimab is a bispecific IgG1 antibody targeting inducible T-cell costimulator (ICOS/CD278) and PD-1. |
Note |
For research use only. Not for use in clinical or therapeutic applications. |