Catalog No. |
TD-HV716016 |
Species reactivity |
Human |
Applications |
Research Grade Biosimilar |
Host species |
Human |
Isotype |
IgG4-IgG1,Lambda |
Expression system |
Mammalian Cells |
Clonality |
Monoclonal |
Target |
OSMRB, IL-31R subunit beta, Oncostatin-M-specific receptor subunit beta, Interleukin-31 receptor subunit beta, IL-31RB, IL-31R-beta, OSMR, IL-31 receptor subunit beta |
Endotoxin level |
Please contact the lab for this information. |
Purity |
>95% purity as determined by SDS-PAGE. |
Purification |
Protein A/G, purified from cell culture supernatant. |
Accession |
Q99650 |
Form |
Liquid |
Storage buffer |
0.01M PBS,pH7.4. |
Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
Alternate Names |
KPL-716,30C6(N73D),BIIB069,BIIB-069,CAS:2243320-83-2 |
Background |
Vixarelimab (KPL-716) is a human anti-oncostatin M (OSM) monoclonal antibody that binds to the beta chain of the OSM receptor and inhibits IL-31 and OSM signalling. Vixarelimab can be used in studies of inflammatory skin diseases such as atopic dermatitis and itchy nodular rash. |
Note |
For research use only. Not for use in clinical or therapeutic applications. |