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抗体药类似物
Research Grade Vixarelimab
All
TD-HV716016_1.jpg
  • CatalogTD-HV716016
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsKPL-716,30C6(N73D),BIIB069,BIIB-069,CAS:2243320-83-2
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Vixarelimab


Catalog No. TD-HV716016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Human
Isotype IgG4-IgG1,Lambda
Expression system Mammalian Cells
Clonality Monoclonal
Target OSMRB, IL-31R subunit beta, Oncostatin-M-specific receptor subunit beta, Interleukin-31 receptor subunit beta, IL-31RB, IL-31R-beta, OSMR, IL-31 receptor subunit beta
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession Q99650
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names KPL-716,30C6(N73D),BIIB069,BIIB-069,CAS:2243320-83-2
Background Vixarelimab (KPL-716) is a human anti-oncostatin M (OSM) monoclonal antibody that binds to the beta chain of the OSM receptor and inhibits IL-31 and OSM signalling. Vixarelimab can be used in studies of inflammatory skin diseases such as atopic dermatitis and itchy nodular rash.
Note For research use only. Not for use in clinical or therapeutic applications.

 

TD-HV716016_1.jpg
Bioactivity
 
SEC-HPLC detection for Research Grade Vixarelimab.