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抗体药类似物
Research Grade Envafolimab
All
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  • CatalogTD-HV974046
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsKN-035,CAS:2102192-68-5
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Envafolimab


Catalog No. TD-HV974046
Species reactivity Human
Applications Research Grade Biosimilar
Host species Chimeric
Isotype (VH-CH2-CH3)2
Expression system Mammalian Cells
Clonality Monoclonal
Target B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession Q9NZQ7
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names KN-035,CAS:2102192-68-5
Background Envafolimab (ASC 22; KN 035) is a recombinant protein of a humanized single-domain anti- PD-L1 antibody. Envafolimab is created by a fusion of the of anti-PD-L1 domain with Fc fragment of human IgG1 antibody. Envafolimab blocks interaction between PD-L1 and PD-1 with an IC50 value of 5.25?nM. Envafolimab has the potential for the research of solid tumors.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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Bioactivity
 
Detects Human CD274/PD-L1/B7-H1 in indirect ELISAs.
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SDS-PAGE
 
SDS-PAGE for Research Grade Envafolimab