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Research Grade Cosibelimab
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- Catalog： TD-HV974066
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： Research Grade Cosibelimab
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规格：
1mg
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价格：
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Research Grade Cosibelimab
| Catalog No. | TD-HV974066 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Human |
| Isotype | IgG1-lambda |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274 |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | Q9NZQ7 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | CK-301,CAS:2216751-26-5 |
| Background | Cosibelimab (CK-301; TG-1501) is a high-affinity, fully human PD-L1-blocking monoclonal antibody that binds PD-L1 and blocks its interaction with PD-1. Cosibelimab has a functional Fc domain and is capable of inducing ADCC and complement-dependent cytotoxicity (CDC)-mediated killing of PD-L1+ cell lines, including lymphoma cells. |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
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SEC-HPLC detection for Research Grade Cosibelimab. |
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Detects CD274/PD-L1/B7-H1 in indirect ELISAs. |