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抗体药类似物
Research Grade Ivuxolimab
All
TD-HW342016_1.jpg
  • CatalogTD-HW342016
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsPF-04518600,CAS:2225940-98-5
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Ivuxolimab


Catalog No. TD-HW342016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Human
Isotype IgG2-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target ACT35 antigen, TXGP1L, TAX transcriptionally-activated glycoprotein 1 receptor, Tumor necrosis factor receptor superfamily member 4, TNFRSF4, OX40L receptor, CD134
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession P43489
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names PF-04518600,CAS:2225940-98-5
Background Ivuxolimab is an OX40 (also known as CD134; TNFRSF4) agonist monoclonal antibody. OX40 is a costimulatory receptor expressed on activated CD4+ and CD8+ T cells. Ivuxolimab shows antitumor activity, with potential immunostimulatory activity.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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Bioactivity
 
Detects CD134/TNFRSF4/OX40 in indirect ELISAs.