抗体
试剂盒
多肽
蛋白
组织芯片
产品中心
Product Center
Research Grade Leronlimab
All
TD-HW412016_1.jpg
- Catalog： TD-HW412016
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： HuPRO-140,PA-14,PRO-140,CAS:674782-26-4
-
规格：
1mg
-
价格：
¥询价
定制服务咨询
Research Grade Leronlimab
| Catalog No. | TD-HW412016 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Humanized |
| Isotype | IgG4-kappa |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | C-C CKR-5, CC-CKR-5, CMKBR5, HIV-1 fusion coreceptor, CHEMR13, CCR5, C-C chemokine receptor type 5, CD195, CCR-5 |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | P51681 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | HuPRO-140,PA-14,PRO-140,CAS:674782-26-4 |
| Background | Leronlimab (PRO 140) is a humanized IgG4 anti-CCR5 monoclonal antibody. Leronlimab inhibits CCR5-mediated HIV-1 viral and lung metastasis in mouse tumor models. Leronlimab can be used for the research of HIV nonalcoholic steatohepatitis (NASH) and cancer. |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
|
|
SDS-PAGE for Research Grade Leronlimab. |