EN
抗体药类似物
Research Grade Trabikibart
All
  • CatalogTD-HW498026
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsCAS:2643974-98-3
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Trabikibart


Catalog No. TD-HW498026
Species reactivity Human
Applications Research Grade Biosimilar
Host species Human
Isotype IgG4-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target Cytokine receptor common subunit beta, IL3RB, IL5RB, CDw131, CD131, CSF2RB, GM-CSF/IL-3/IL-5 receptor common beta subunit
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession P32927
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names CAS:2643974-98-3
Background Trabikibart (CSL311), a βc (CSF2RB)-specific, fully human monoclonal antibody, binds to a unique epitope that is specific to the cytokine-binding site of the human βc receptor. Trabikibart has picomolar binding affinity for the human βc receptor. Trabikibart is a potent inhibitor of the combined effects of IL-3, GM-CSF and IL-5 on the survival of eosinophils. Trabikibart has the potential for chronic inflammatory diseases research.
Note For research use only. Not for use in clinical or therapeutic applications.