TD-HW564056

Perenostobart(TD-HW564056) is a research-grade recombinant antibody targetingCD39. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.

Human

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Human

IgG4-kappa

Monoclonal

Ecto-ATP diphosphohydrolase 1, NTPDase 1, ENTPD1, Ecto-ATPase 1, Ecto-apyrase, Ecto-ATPDase 1, Ectonucleoside triphosphate diphosphohydrolase 1, CD39, Lymphoid cell activation antigen

Please contact the lab for this information.

>95% purity as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

P49961

Liquid

0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

2643331-31-9

Eurestobart is a humanized IgG1κ antibody targeting ENTPDase.• CD39 and CD73 in immunity and inflammation., PMID:23601906• Ectonucleoside triphosphate diphosphohydrolase-1 (CD39) impacts TGF-β1 responses: insights into cardiac fibrosis and function following myocardial infarction., PMID:36240436• Favorable function of Ectonucleoside triphosphate diphosphohydrolase 1 high expression in thyroid carcinoma., PMID:34465393• Ectonucleoside triphosphate diphosphohydrolase-1 (E-NTPDase1/CD39) as a new prognostic marker in chronic lymphocytic leukemia., PMID:24684231• Revealing and harnessing CD39 for the treatment of colorectal cancer and liver metastases by engineered T cells., PMID:37399271• ATP signaling and NTPDase in Systemic Lupus Erythematosus (SLE)., PMID:30803848• Heterologous cell-cell interactions: thromboregulation, cerebroprotection and cardioprotection by CD39 (NTPDase-1)., PMID:14675084• Role of CD39 (NTPDase-1) in thromboregulation, cerebroprotection, and cardioprotection., PMID:15852226• CD39/ectonucleoside triphosphate diphosphohydrolase 1 provides myocardial protection during cardiac ischemia/reperfusion injury., PMID:17909107• Ectonucleoside triphosphate diphosphohydrolase 1 and 5'-nucleotidase ecto gene polymorphisms and acute cellular rejection after liver transplantation., PMID:32248630

SDS-PAGE for Research Grade Perenostobart

For research use only. Not suitable for clinical or therapeutic use.