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抗体药类似物
Research Grade Brontictuzumab
All
TD-HW570016_1.jpg
  • CatalogTD-HW570016
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsOMP-52M51,CAS:1447814-75-6
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Brontictuzumab


Catalog No. TD-HW570016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype IgG2-lambda
Expression system Mammalian Cells
Clonality Monoclonal
Target hN1, TAN1, NEXT, NICD, Notch 1, Neurogenic locus notch homolog protein 1, Translocation-associated notch protein TAN-1, NOTCH1
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession P46531
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names OMP-52M51,CAS:1447814-75-6
Background Brontictuzumab (OMP 52M51) is a monoclonal antibody (MAb) that inhibits Notch1 signal. Brontictuzumab selectively binds the negative regulatory region of the Notch1. Brontictuzumab inhibits tumor cell proliferation. Brontictuzumab can be used in the research of leukemia and lymphoma.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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Bioactivity
 
SEC-HPLC detection for Research Grade Brontictuzumab.