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抗体药类似物
Research Grade Galiximab
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TD-HW630016_1.jpg
  • CatalogTD-HW630016
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsIDEC-114,CAS:357613-77-5
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Galiximab


Catalog No. TD-HW630016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Chimeric
Isotype IgG1-lambda
Expression system Mammalian Cells
Clonality Monoclonal
Target CD80, BB1, T-lymphocyte activation antigen CD80, CD28LG, B7, CD28LG1, LAB7, Activation B7-1 antigen, CTLA-4 counter-receptor B7.1
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession P33681
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names IDEC-114,CAS:357613-77-5
Background Galiximab (IDEC 114) is a primatized immunoglobulin G1 (IgG1) lambda monoclonal antibody directed against the CD80 antigen and blocks CD80–CD28 binding. Galiximab has variable regions are primatized (cynomologous monkeys), and the constant regions are human. Galiximab can be used in research of B-cell lymphoma.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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Bioactivity
 
Detects Human CD80/B7-1 in indirect ELISAs.