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Research Grade Lebrikizumab
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TD-HW632026_1.jpg
TD-HW632026_2.jpg
- Catalog： TD-HW632026
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： MILR1444A, PRO301444, CAS: 953400-68-5
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规格：
1mg
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价格：
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Research Grade Lebrikizumab
| Catalog No. | TD-HW632026 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Humanized |
| Isotype | IgG4-kappa |
| Expression system | Mammalian Cells |
| Species | Human |
| Clonality | Monoclonal |
| Target | IL13, NC30, Interleukin-13, IL-13 |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P35225 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Alternate Names | MILR1444A, PRO301444, CAS: 953400-68-5 |
| Background | Lebrikizumab (TNX-650) is an IgG4 humanized anti-interleukin-13 (IL-13) mAb with anti-itch effects that specifically binds to IL-13 in a non-receptor binding domain and inhibits its function. Lebrikizumab inhibits the IL-13 driven Th2 inflammatory response and blocks the signaling of IL-4Rα/IL-13Rα1. Lebrikizumab can be used for the research of asthma, atopic dermatitis and neuroinflammatory diseases. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
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Detects Human IL13 in indirect ELISAs. |
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SDS-PAGE for Research Grade Lebrikizumab. |