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Research Grade Ascrinvacumab
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- Catalog： TD-HW651016
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： PF-03446962,CAS:1463459-96-2
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规格：
1mg
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价格：
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Research Grade Ascrinvacumab
| Catalog No. | TD-HW651016 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Human |
| Isotype | IgG2-kappa |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | Serine/threonine-protein kinase receptor R3, ACVRL1, Activin receptor-like kinase 1, ALK-1, ACVRLK1, ALK1, SKR3, TGF-B superfamily receptor type I, TSR-I |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | P37023 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | PF-03446962,CAS:1463459-96-2 |
| Background | Ascrinvacumab (PF-03446962) is a human IgG2 monoclonal antibody targets ALK-1. Ascrinvacumab shows binding efficiency with human ALK1 with a Kd value of 7 nM. Ascrinvacumab can be used for the research of hepatocellular carcinoma (HCC). |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
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SEC-HPLC detection for Research Grade Ascrinvacumab. |
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Detects ACVRL1/ALK-1 in indirect ELISAs. |
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SDS-PAGE for Research Grade Ascrinvacumab. |