抗体
试剂盒
多肽
蛋白
组织芯片
产品中心
Product Center
Research Grade Orilanolimab
All
TD-HX061016_1.jpg
TD-HX061016_2.jpg
- Catalog： TD-HX061016
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： SYNT-001,CAS:2066544-85-0
-
规格：
1mg
-
价格：
¥询价
定制服务咨询
Research Grade Orilanolimab
| Catalog No. | TD-HX061016 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Chimeric |
| Isotype | IgG4-kappa |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | IgG Fc fragment receptor transporter alpha chain, IgG receptor FcRn large subunit p51, FcRn, FCGRT, FCRN, Neonatal Fc receptor |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | P55899 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | SYNT-001,CAS:2066544-85-0 |
| Background | Orilanolimab (SYNT001) is a humanized, de-immunized and FcRn-blocking monoclonal antibody. Orilanolimab blocks the interaction between FcRn and the Fc portion of IgG molecules. Orilanolimab impedes IgG IC activation of the FcRn-mediated adaptive immune function. And Orilanolimab disrupts the associated pathways related to IgG homeostasis and innate and adaptive immunity. |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
|
|
SEC-HPLC detection for Research Grade Orilanolimab. |
|
|
SDS-PAGE for Research Grade Orilanolimab. |