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Research Grade Zolbetuximab
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- Catalog： TD-HX126016
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： Claudin18.2,GC-182,IMAB-362,IMAB362,Claudiximab,CAS:1496553-00-4
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规格：
1mg
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价格：
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Research Grade Zolbetuximab
| Catalog No. | TD-HX126016 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Chimeric |
| Isotype | IgG1-kappa |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | Claudin-18, CLDN18 |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | P56856 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | Claudin18.2,GC-182,IMAB-362,IMAB362,Claudiximab,CAS:1496553-00-4 |
| Background | Zolbetuximab (IMAB362) is a monoclonal antibody targeting Claudin-18.2. Zolbetuximab mediates specific killing of Claudin-18.2-positive cells through immune effector mechanisms. Zolbetuximab can be used for the research of gastrointestinal adenocarcinomas and pancreatic tumors. |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
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SEC-HPLC detection for Research Grade Zolbetuximab. |
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Flow-cytometry using anti-human Claudin18.2 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human Claudin18.2 monoclonal antibody (Catalog TD-HX126016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, AF647 (abinScience: TD-HF690324) and cells analysed on a NovoCyte Flow Cytometer. |
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SDS-PAGE for Research Grade Zolbetuximab. |